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  1. The most highly radioresistant tumour of the following is (a) Fibrosarcoma (b) Embryonal carcinoma (c) Squamous cell carcinoma (d) Lymphosarcoma (e)Lympho-epithelioma
  2. An encapsulated rubbery breast tumour is most likely a (a) Scirhous Carcinoma (b) Medullary Carcinoma (c) Colloid Carcinoma (d) Fibroadenoma (e) Fibrosarcoma
  3. A tumor arising in a burn scar is most likely to be (a) Squamous cell carcinoma (b) Basal cell carcihoma (c) Malignant melanoma (d) Sweat gland adenocarcinoma
  4. Chronic constrictive pericarditis usually results from (a) Rheumatic fever (b) Myocardial inrarction (c) Tuberculosis (d) Emphysema
  5. Volvulus occurs most frequently in the (a) Jejunum (b) Leum (c) Region of ileocecal valve (d) Transverse colon (e) Sigmoid colon
  6. ''Thyroid '' appearance of renal tubules is considered typical of (a) Chronic pyelonephritis (b) Chronic glomerulonephritis (c)Arteriolar nephrosclerosis (d) Malignant hyperrtension (e) Diabetic nephropathy
  7. Cancer cells derive their energy primarily from (a) Aerobic glycolysis (b) Anaerobic glycolysisi (c) Utilisation of nitrogen (d) Utilisation of carbohydrate (e) Utilisation of fat
  8. The occurrence of caseation in a tuberculous lesion is evidence of (a) Over whelming infection (b) Hypersensitivity (c) Encapsulation (d) Successful resistance (e) Besling
  9. In the female bony metastases most often originate from carcinoma of the (a) Breast (b) Endometrium (c) Ovary (d) Cervix (e) Colon
  10. 10.Maccalum's patch is found in (a) Mitral stenosis (b) Mitral insufficiency (c) Systemic lupus erythematosis (d) Acute rheumatic fever (e) Nonee of these
  11. Periglomerular fibrosis is coonsidered typical of (a) Chronic pyelonephritis (b) Chronic glomerulonephritis (c) Arterio nephrosclerosis (d) Malignant hypertension
  12. Leather bottle stomach is the result of (a) Achlorhydria (b) Hypertrophic gastritis (c) Ulcerative carcinooma (d) Diffuse carcinoma (e) Polypoid carcinoma
  13. The valves most commonly involved in rheumatic heart disease (a) Mitral and tricuspid (b) Tricuspid and pulmonic (c) Pulmonic and abrtic (d) Mitral & pulmonic (e) Mitral and aortic
  14. A reliable screening test for platelet function (a) Prothrombin time (b) Clot retraction test (c) Clotting time (d) thrombin time
  15. The following conditions ar accepted as precancerous EXCEPT (a) Polyposis of the colon (b) Ulcerative colitis (c) Regional ileitis (d) Pigmentary cirrhosis
  16. The L.E. cell is positive in all the following conditions EXCEPT (a) Rheumatoid arthritis (b) Systemic lupus erythematosus (c) Penicillin reaction (d) Hashimoto's disease
  17. Lipid crystals are seen in the epithelial cells in the urine in (a) Porphyrias (b) Haemoglobinuria (c) Cytomegalic inculsion disease (d) Nephrotic syndrome
  18. Workers in vinyl chloride industry are known to develop (a) Adenocarcinoma of the lung (b) Angiosarcoma of the liver (c) Polyposis of the colon (d) Angiofibroma of the nose
  19. All of the following are embryonal tumoours EXCEPT (a) Ameloblastoma (b) Medulloblastoma (c) Retinoblastoma (d) Nephroblastoma
  20. Adenocarcinoma of the urinary bladder is seen in (a) Ectopia Vesicae (b) Urolithiasis (c) Recurrent cystitis (d) All of the above
  21. Fibrinoid necrosis is the hall mark of (a)Gouty tophi (b) diabetic vasculopathy (c) Malignant hypertension (d) Endarteritis obliterans (
  22. Mucosal immunity is mediated through (a) Ig E (b) Secretory IG A (c) Ig G (d) All of the above
  23. Ferruginous bodies result from (A) Sarcodosis (B) Silicosis (C) Tuberculosis (D) Asbestosis (E) Beryllosis
  24. Which of the following cell type is not a part of the reciculoendothelial system (A) Kupffer cells (B)Alveolar macrophages (C) Histiocytes (D)Fibroblast (E)Monocytes
  25. 'Midzonal necrosis' in liver lobules is seen in (A) Yellow fever (B)Phosphorus poisoning (C)Eclampsia (D)Cardiac failure (E) Viral hepatitis.
  26. 'Wear & tear' pigment of the body is (A) Lipochrome (B)Ferritin (C)Hemosiderin (D)Melanin (E) Bilirubin
  27. 'Laennec's cirrhosis' is associated with (A) Drug toxicity (B)Hepatitis B virus (C)Chronic alcoholism (D)Wilson's disease (E) Hemochromatosis
  28. 'Klatskin tumor' are carcinoma located at (A) Bile duct (B)Ampulla of vater (C)Junction of hepatic ducts (D) Cystic duct (E) Junction of cystic duct and bile duct.
  29. Confirming the diagnosis of secondary amyloidosis, the biopsy is usually taken from (A) Rectum (B)Ileum (C)Kidney (D)Lung
  30. Epstein Barr virus cause (A) Infectious ononucleosis (B)Nasopharyngeal carcinoma (C) Burkitt's lymphoma (D)All of the above
  31. Pathognomic enal lesion of diabetes mellitus is (A) Nodeular glomerulosclerosis (B)Diffuse glomerulosclerosis (C)Arteriolosclerosis (D) Pyelonephritis.
  32. Metastatic calcification occurs in all except (A) Sarcoidosis (B) Milk alkali syndrome (C)Hyperparathyroidism (D)Leiomyoma uterus
  33. Red infarcts are seen in all except (A)Venous obstruction (B)Tissues with a double circulation (C) In solid organs (D) Previously congested tissues.
  34. Diseases associated with HLA-B8 antigen are all except (A) Addison's disease (B) Psoriasis vulgaris (C) Celiac disease (D) Thyrotoxicosis.
  35. There is increased risk of acute leukemia in all except (A) Down's syndrome (B) Bloom's syndrome (C) Fanconi's anemia (D) PNH
  36. Microangiopathic hemolytic anemia occurs in (A) DIC (B) Hemolytic-uremic syndrome (C) Disseminated malignancy (D) All of the above.
  37. Lymphocytic leukemoid reaction is seen in all (A) Tuberculosis (B) Pertussis (C) Infectious mononucleosis (D) Visceral larva migrans.
  38. Which of the following condition leads to primary gout (A) Lesch-Nyhan syndrome (B)Chronic renal disease (C) Leukemia (D) Lead nephropathy.
  39. Most common type of actinomycosis is (A) Thoracic (B) Abdominal (C)Cervicofacial (D) None of the above.
  40. Specific marker for vascular endothelium is most sensitive to (A) Dohle body (B) Weibel Palade body (C) Asteroid body (D) Schaumann body.
  41. 'Reversed coarctation' of aorta results from (A) Giant cell arteritis (B) Takayasu's arteritis (C) Polyarteritis nodosa (D) Buerger's disease.
  42. Least commonly affected value in rheumatic fever is (A) Aortic (B) Mitral (C)Pulmonary (D) Tricuspid
  43. Most common primary tumour of heart is (A) Myxoma (B) Lymphosarcoma (C) Rhabdomyoma (D) Rhabdomyosarcoma.
  44. 'Curschmann's spirals' are seen in (A) Chronic bronchitis (B)Bronchial asthma (C) Bronchiectasis (D) Atelectasis.
  45. The commonest site of metastases in carcinoma of lung is (A) Liver (B)Kidney (C) Adrenal (D) Bone
  46. 'Hypertrophic gastropathy' is characteristic of (A) Zollinger Ellison syndrome (B) Goodpasture's syndrome (C) Chronic superficial gastritis (D) Carcinoma stomach
  47. Commonest site of colonic diverticula is (A) Ascending colon (B) Descending colon (C) Transverse colon (D) Sigmoid colon.
  48. Commonest organism causing acute pyelonephritis is (A) E.coli (B) Proteus (C) Staph. Aureus (D) Strep. Fecalis
  49. LDH3 is elevated in (A) Acute viral hepatitis (B) Myocardial infarction (C) Pulmonary infarction (D) Acute hemolytic anemia.
  50. Post-transfusion hepatitis is usually caused by (A) HAV (B) HBV (C) Non-A-Non B hepatitis virus (D) ECHO virus.
  51. Fetal Hb cpnsists of (A) 2 alpha & 2 beta chains (B)2 alpha & 2 delta chains (C) 2 alpha & 2 gamma chains (D) 2 beta & 2 gamma chains
  52. Commonest site of origin of carcinoma of prostate is (A) Median lobe (B) Posterior lobe (C) Anterior lobe (D) Lateral lobe
  53. 'Caseation necrosis' is found in (A) Tuberculosis (B) Sacroidosis (C) Rheumatoid arthritis (D) Rheeumatic carditis.
  54. Which type of Hodgkin's lymphoma is associated with best prognosis (A) Lymphocyte predominance (B) Lumphocyte depletion (C) Nodular sclerosis (D) Mixed cellularity.
  55. Heart failure cells are present in (A) Lung (B) Liver (C) Kidney (D) Heart.
  56. Dystophic calcification is seen in (A) Atherosclerotic plaques (B) Hyperparathyroidism (C) Multiple myeloma (D) Milk alkali syndrome.
  57. All are features of herediatary spherocytosis except (A) Autosomal dominant inheritance (B) Increased MCHC (C) Decreased surface area(D) MCV increased.
  58. Normal free plasma hemoglobin is (A) 0.1mg% (B) 0.6 mg% (C) 0.1g% (D) 0.6 g%
  59. Which of the following is not a tumor marker (A)B2 macroglobulin (B) Calcitonin (C) a-Fetoprotein (D) Gastrin.
  60. Principal chemical mediator of enhanced vessel permeability is (A) Cationic protein (B) Beta glucuronidase (C) Acid phosphatase (D) Leukotriene C4
  61. Type of pericarditis seen in RHD is (A) Serous (B) Purulent (C) Serofibrinons (D) Haemorrhagic.
  62. All are labile cells except (A) Bone marrow cells (B) Intestinal mucosa (C) Epithelial cells of skin (D) Liver cells.
  63. Progressive pulmonary hypertension is responsible for the fatal outcome of (A) Tetralogy of Fallot (B) Hypoplastic left heart syndrome (C) Patent ductus arteriosus (D) Postductal coarctation of aorta.
  64. Which of the following statement about 'plasma membrane' is not true. (A) Fluid mosaic model of cell membrane was introduced by Singer and Nicolson (B) Membrane proteins form 60% of cell membrane (C) Peripheral membrane proteins are non essential to the basic structures of biological membranes (D)Peripheral proteins are involved in metabolite and ion transport.
  65. Defective chemotaxis is present in all except (A) Diabetes mellitus (B) Sarcoidosis (C) Chronic renal failure (D) Chronic granulomatous disease.
  66. Tissue cells most sensitive to ischemic hypoxia are (A) Cerebral cortical neurons (B) Cerebellar neurons (C) Myocardial cells (D) Skeletal muscle cells.
  67. All are confirmatory laboratory findings of Kinefelters' syndrome except (A) Positive X- chromatin (B) Reduction of sperm in seminal fluid (C) Lower serum testosterone level (D) Decreased urinary excretion of FSH.
  68. Which of the following statement about SLE is not true (A) More common in females (B) Antinuclear anatibody to double stranded DNA is diagnostic (C) There is erosive synovitis with joint deformity (D) Onion skin leisons are seen in spleen.
  69. Glisson's capsule encloses (A) Liver (B) Spleen (C) Kidney (D) Heart.
  70. Commonest benign tumor of liver is (A) Cavernous hemangioma (B) Bile duct adenoma (C) Mesenchymal hamartoma (D) Liver cell adenoma.
  71. Which of the following organ is most severty affected in shock (A) Heart (B) Lung (C) Liver (D) Kidney.
  72. Glomus tumor arises from (A) Ectoderm (B) Mesoderm (C) Endoderm (D) Neuroectoderm
  73. All of the following are phagocytes except (A) Lymphocytes (B) Neutrophils (C) Kupffer cells (D) Sinusoidal cells lining the lymph nodes.

 

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